Proliferated cell lines and uses thereof

专利名称：Proliferated cell lines and uses thereof发明人：Thomas B. Freeman,Pablo Caviedes,Raul

Caviedes,Paul R. Sanberg,Don F. Cameron

申请号：US10359854申请日：20030207

公开号：US20030232752A1公开日：20031218

专利附图：

摘要：The subject invention pertains to tumor cell lines useful for increasing theproliferation potential of any human or animal cell in culture, thereby providingimmortalized or continuous cell lines and cultures. The invention also concerns

proliferation factors, and compositions containing the factors, which are capable ofincreasing the proliferation potential of any human or other animal cell in culture. Thesubject invention further pertains to a method for proliferation cells in culture bycontacting cells with the proliferation factors. The proliferated cells can range inplasticity and can include, for example, blast cells, fertilized ova, non-fertilized gametes,embryonic stem cells, adult stem cells, precursor or progenitor cells, and highlyspecialized cells. Optionally, the cells can be induced to cease proliferation. The

proliferation cells of the subject invention are useful for cell therapy, cell/gene therapy,biological production of molecules, and as in vitro models for research, toxicity testing,and drug development.

申请人：FREEMAN THOMAS B.,CAVIEDES PABLO,CAVIEDES RAUL,SANBERG PAULR.,CAMERON DON F.

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