专利名称:SUBSTITUTED IMIDAZOPYRIDINE AND
TRIAZOLOPYRIDINE ANALOGS AS POSITIVEALLOSTERIC MODULATORS OF
MUSCARINIC ACETYLCHOLINE RECEPTORM1
发明人:P. Jeffrey Conn,Craig W. Lindsley,Kyle A.
Emmitte,Changho Han,Julie L. Engers,AaronM. Bender
申请号:US15568936申请日:20160422
公开号:US20180118746A1公开日:20180503
摘要:In one aspect, the invention relates to substituted imidazopyridine and
triazolopyridine analogs, derivatives thereof, and related compounds, which are useful aspositive allosteric modulators of the muscarinic acetylcholine receptor M(mAChR M);synthesis methods for making the compounds; pharmaceutical compositions comprisingthe compounds; and methods of treating neurological and psychiatric disordersassociated with muscarinic acetylcholine receptor dysfunction using the disclosedcompounds and compositions. This abstract is intended as a scanning tool for purposesof searching in the particular art and is not intended to be limiting of the presentinvention.
申请人:Vanderbilt University
地址:Nashville TN US
国籍:US
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