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SUBSTITUTED IMIDAZOPYRIDINE AND TRIAZOLOPYRIDINE A

来源:易榕旅网
专利内容由知识产权出版社提供

专利名称:SUBSTITUTED IMIDAZOPYRIDINE AND

TRIAZOLOPYRIDINE ANALOGS AS POSITIVEALLOSTERIC MODULATORS OF

MUSCARINIC ACETYLCHOLINE RECEPTORM1

发明人:P. Jeffrey Conn,Craig W. Lindsley,Kyle A.

Emmitte,Changho Han,Julie L. Engers,AaronM. Bender

申请号:US15568936申请日:20160422

公开号:US20180118746A1公开日:20180503

摘要:In one aspect, the invention relates to substituted imidazopyridine and

triazolopyridine analogs, derivatives thereof, and related compounds, which are useful aspositive allosteric modulators of the muscarinic acetylcholine receptor M(mAChR M);synthesis methods for making the compounds; pharmaceutical compositions comprisingthe compounds; and methods of treating neurological and psychiatric disordersassociated with muscarinic acetylcholine receptor dysfunction using the disclosedcompounds and compositions. This abstract is intended as a scanning tool for purposesof searching in the particular art and is not intended to be limiting of the presentinvention.

申请人:Vanderbilt University

地址:Nashville TN US

国籍:US

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