专利名称：Analytical method for the selective
determination of sialic glycolipid complexes
发明人：Bela Szajani,Anna Gesztesi nee
Koszegi,Ferenc Pribek,Bela Schumann,JolanBabarczi,Edit Kinczel,Iren Milovan,Edit Siklosinee Patay,Katalin Ivony nee Kladiva
申请号：US07/689286申请日：19910603公开号：US05275952A公开日：19940104
摘要：A method for the selective determination of sialic acid- carrying glycolipidcomplexes in blood, in which the serum is diluted with water, then extracted with a water-immiscible organic solvent or solvent mixture to remove neutral lipids, a lipoproteinfraction containing sialic acid- carrying glycolipids is precipitated from the aqueous phase,the precipitated fraction is redissolved, and the sialic acid content of the solution or theamount and quality of the sialic acid- carrying glycolipid are determined by a methodknown per se. A water- soluble salt of a monovalent, bivalent or trivalent metal otherthan alkali metal is used as a precipitating agent in an amount corresponding to a finalmetal ion concentration of 0.005-0.1 mole/l in the mixture, and precipitation is performedat a pH of 1.5 to 8.0.
申请人：REANAL FINOMVEGYSZERGYAR
代理人：Herbert Dubno,Jonathan Myers
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